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目的探讨新生儿重症监护病房(NICU)早产儿脑室内出血(IVH)的发病因素及防治。方法回顾分析2000年1月至2006年3月我院NICU早产儿临床资料,生后3～7d内头颅B超检查情况。结果480例早产儿,脑室内出血160例,发生率达33.3%,与出生胎龄、出生体重呈负相关,与窒息、缺氧、感染、贫血等并发症程度呈正相关。结论IVH与胎龄、出生体重、窒息、缺氧、感染、贫血、机械通气密切相关,综合防治可减少IVH发生率,提高早产儿,尤其是极低体重儿的抢救成功率、避免或减少后遗症的发生。
Objective To investigate the pathogenesis and prevention of intraventricular hemorrhage (IVH) in neonatal intensive care unit (NICU) premature infants. Methods The clinical data of NICU preterm children in our hospital from January 2000 to March 2006 were analyzed retrospectively. The results of cranial ultrasound examination within 3 ~ 7 days after birth were retrospectively analyzed. Results Among the 480 preterm infants, intraventricular hemorrhage was found in 160 cases with the incidence of 33.3%. It was negatively correlated with gestational age and birth weight. It was positively correlated with the degree of complications such as asphyxia, hypoxia, infection and anemia. Conclusions IVH is closely related to gestational age, birth weight, asphyxia, hypoxia, infection, anemia and mechanical ventilation. Integrated prevention and treatment can reduce the incidence of IVH and improve the success rate of rescue in preterm infants, especially those with very low birth weight, and avoid or reduce sequelae happened.