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目的探讨 ABO血型及其与吸烟交互作用后与肺癌的相关性。方法肺癌病例 143例 ,年龄、性别匹配的对照 12 1例 ;血清学方法检测血型 ,面访或查阅病历调查 ,分层分析血型与吸烟的交互作用。结果单 B型血者与肺癌无显著性联系 ,单吸烟者则联系显著 ,OR值 2 .0 9,同时具有 B型血并吸烟 ,则联系非常显著 ,其 OR值达 5 .88。结论 B型血是肺癌的可能易感标志 ,并与吸烟具有协同作用
Objective To explore the correlation between ABO blood type and lung cancer after its interaction with smoking. Methods A total of 143 cases of lung cancer were included in the study, including age- and sex-matched controls, 121 patients; serum samples were tested for blood type, face-to-face or medical records were investigated, and the interaction between blood type and smoking was stratified. Results There was no significant association between B-type blood and lung cancer. The single-smoker had a significant association with an OR of 2.0 and had B-type blood and smoking. The association was very significant, with an OR of 5.88. Conclusion B-type blood is a possible susceptibility marker of lung cancer and has a synergistic effect with smoking