本文报道1例毛细胞性白血病合并脑膜白血病。患者男性,62岁。主诉1个多月来前额进行性疼痛,活动颈部时加重,此外无其它伴随症状。体检发现脾肿大,神经系统检查阴性。实验室检查:血白细胞2800/mm~3,血小板66,000/mm~3,血红蛋白13.3g％,网织红细胞1.9％,血清结合珠蛋白18.7mg/dl(正常25～187mg/dl)。肝脾扫描发现重度脾肿大。周围血涂片发现大量染色质疏松均匀排列的不成熟核及绒毛样胞浆足突的异常单个核细胞。骨髓活检发现同样的 This article reports a case of hairy cell leukemia combined with meningocytic leukemia. Male patient, 62 years old. Chief complaint more than a month to forehead pain, aggravating neck activity, in addition to no other symptoms. Physical examination found splenomegaly, negative neurological examination. Laboratory tests: blood leukocyte 2800 / mm ~ 3, platelet 66,000 / mm ~ 3, hemoglobin 13.3g%, reticulocyte 1.9%, serum haptoglobin 18.7mg / dl (normal 25 ~ 187mg / dl). Liver and spleen scan found severe splenomegaly. Peripheral blood smear found a large number of loosely arranged chromatin immature nuclei and villous cytoplasm of the foot process of abnormal mononuclear cells. Marrow biopsy found the same