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目的：探讨口腔矫治器治疗对阻塞性睡眠呼吸暂停低通气综合征患者焦虑抑郁情绪及心理状态的影响。方法对48名轻、中度OSAHS患者采用下颌前移矫治器进行治疗，在治疗前及治疗6个月后采用多导睡眠图（PSG）监测、白天过度嗜睡（EDS）、症状自评量表（SCL-90）、焦虑自评量表（SAS）、抑郁自评量表（SDS）对治疗的疗效及患者的心理状况进行评分并进行统计学分析。结果 OSAHS患者的主客观症状均有显著改善；患者治疗前SCL-90各因子评分均高于中国正常成人常模，在戴用口腔矫治器治疗6个月后，SCL-90各因子及焦虑、抑郁评分显著降低，差异有统计学意义（P＜0．05）。结论 OSAHS患者心理健康水平较低，口腔矫治器治疗可以有效地改善OSAHS患者的心理状况。“,”Objective To explore the influence of oral appliance therapy on the anxiety,depression and psychological stateofobstructivesleepapnea-hypopneasyndrome(OSAHS)patients.Methods 48mildormoderateOSAHS patients were treated with oral appliance.The PSG examination,ESS,SCL-90,SAS and SDS questionnaire were adopted to evaluate efficacy of oral appliance,anxiety,depression and psychological state in all patients before the treat-ment and 6 months after the treatment.Results The objective and subjective symptoms of OSAHS patients were sig-nificantly reduced.The scores of psychological state before the treatment were significantly higher than the average scores of Chinese norm.After 6 months treatment,the scores of anxiety,depression and psychological state in OSAHS were significantly reduced compared to those of pre-treatment (P<0.05).Conclusion OSAHS patients are more anx-ious and depressive than the normal.Oral appliance treatment can conduce to mental rehabilitation of OSAHS patients.