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目的了解经阴道配子输卵管移植治疗非输卵管性不孕症（子宫内膜异位症、男性少弱精症、不明原因不孕等）的效果。方法对引例（对个周期）不孕症患者分别采用（１）绝经期促性腺激素（ｈＭＧ）ｈＣＧ（７个周期）：（２）卵泡刺激素（ＦＳＨ）／ｈＭＧ／ｈＣＧ（２）个周期）；（３）短方案促性腺激素释放激素激动剂（ＧｎＲＨ－ａ）／ｈＭＧ／ｈＣＧ（２个周期）；（４）长方案ＧｎＲＨ－ａ／ＦＳＨ／ｈＭＧｈＣＧ（１２个周期）进行超促排卵。阴道超声下取卵，经阴道向输卵管内插管注人卵母细胞和精子，用ｈＣＧ或黄体酮维持黄体功能。结果平均每周期植人卵子数为（３．３±２．１）个（１～８个）；５例妊娠，周期妊娠率为引７％．其中宫内妊娠４例，输卵管妊娠１例。２例胚胎停止发育，２例继续妊娠已达３０～３４周。结论经阴道配子输卵管移植是一种操作较简单而有效的助孕技术，与经腹腔镜配子输卵管移植相比，价格低廉，无需麻醉，可用于治疗输卵管正常的多种不孕症。
Objective To understand the effect of transvaginal gamete tubal transplantation on non-tubal infertility (endometriosis, oligozoospermia, unexplained infertility, etc.). Methods (1) hCG (7 cycles) of menopausal gonadotrophs (hMG) and 2 cycles of follicle stimulating hormone (FSH) / hMG / hCG ); (3) short regimen of GnRH-a / hMG / hCG (2 cycles); (4) long regimen of GnRH-a / FSH / hMGhCG . Ovum vaginal ultrasound, transvaginal tubal intubation of human oocytes and sperm injection, with hCG or progesterone maintain luteal function. Results The average number of eggs per week was (3.3 ± 2.1) (1 ~ 8). In 5 cases of pregnancy, the pregnancy rate was 7%. 4 cases of intrauterine pregnancy, tubal pregnancy in 1 case. 2 cases of embryo stop development, 2 cases of pregnancy has reached 30 to 34 weeks. Conclusion Transvaginal gamete tubal transplantation is a relatively simple and effective method of assisted pregnancy. Compared with laparoscopic tubal tubal transplantation, the transvaginal gamete tubal transplantation is inexpensive and without anesthesia and can be used to treat various infertility with normal fallopian tube.