随着社会进步和科学技术日新月异,孕早期无创性的产前诊断愈来愈受重视。国内外学者对孕妇外周血特别是早孕期宫颈胎儿滋养细胞应用于产前诊断来检测胎儿性别、非整倍体异常、单基因遗传病等进行了大量的实验研究,以期使这种早期,简便,无创性产前诊断的方法应用于临床。而从宫颈处获取的胎儿细胞量远高于从母体外周血获得的,结合现有的细胞检测技术,使其更具应用潜力。 With the social progress and the ever-changing science and technology, noninvasive prenatal diagnosis of early pregnancy is more and more attention. Domestic and foreign scholars have carried out a large number of experimental studies on pregnant women’s peripheral blood, especially early pregnancy cervical fetal trophoblastic cells used in prenatal diagnosis to detect fetal sex, aneuploidy, single gene disease, etc., in order to make this early, simple , Noninvasive prenatal diagnosis method used in clinical. The amount of fetal cells obtained from the cervix is ​​much higher than that obtained from the mother’s peripheral blood, and combined with the existing cell detection technology to make it more potential.