论文部分内容阅读
目的:观察米非司酮治疗子宫肌瘤的临床效果。方法:选择114例子宫肌瘤患者给予口服米非司酮25 mg治疗,1次/d,3个月为1个疗程,定期彩色多普勒超声检查服药前后子宫及肌瘤大小的变化,并与治疗前比较。结果:114例患者服药后子宫和肌瘤的平均体积均较服药前明显缩小,口服米非司酮可引起闭经、改善贫血;停药后月经复潮;可使经量减少、经期缩短;子宫体积和肌瘤体积缩小,治疗前后对比,差异有统计学意义(P<0.05)。结论:米非司酮对子宫肌瘤治疗有一定效果,不良反应少,是安全、简便、有效的治疗子宫肌瘤的药物,值得临床推广应用。
Objective: To observe the clinical effect of mifepristone in treating uterine fibroids. Methods: 114 cases of uterine fibroids were treated with oral mifepristone 25 mg once daily for 3 months as a course of treatment. The changes of uterine and fibroid size before and after taking the medicine were examined by regular color Doppler sonography. Compared with before treatment. Results: The average volume of uterus and fibroids in 114 patients was significantly reduced compared with that before treatment. Oral mifepristone can cause amenorrhea and improve anemia. After menstruation, menstruation reoccurred. The menstrual flow could be reduced and the menstrual period shortened. The uterus Volume and fibroids shrink, before and after treatment, the difference was statistically significant (P <0.05). Conclusion: Mifepristone treatment of uterine fibroids have a certain effect, less adverse reactions, is a safe, simple and effective treatment of uterine fibroids medicine, worthy of clinical application.