口腔扁平苔藓(OLP)是一种发生于口腔黏膜的慢性自身免疫性疾病,可伴有皮肤、生殖道黏膜,指甲以及毛发的病损。其组织病理学特征是上皮下淋巴细胞浸润带的形成、基膜的断裂和基底细胞液化变性。本文就CD4+/CD8+T细胞与OLP,记忆T细胞/原始T细胞与OLP,Th1、Th2、Th9、Th17细胞与OLP,调节性T细胞与OLP等研究进展作一综述。 Oral lichen planus (OLP) is a chronic autoimmune disease that occurs in the oral mucosa and may be associated with lesions of the skin, genital mucosa, nails and hair. Its histopathological features are the formation of subepithelial lymphocyte infiltration zone, rupture of basement membrane and liquefaction of basal cells. In this paper, the progress of CD4 + / CD8 + T cells and OLP, memory T cells / primitive T cells and OLP, Th1, Th2, Th9, Th17 cells and OLP, regulatory T cells and OLP were reviewed.