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目的:探讨妊娠期高血压疾病的临床结局与血清胱抑素C的关联性。方法:将200例妊娠期高血压疾病患者设为观察组,并将其分为妊娠期高血压病组、轻度子痫前期组、重度子痫前期组及子痫组。选择同期的100例健康孕妇作为对照组。测定所有孕妇的血清胱抑素C水平。结果:观察组中各小组中发生不良结局者血清胱抑素C水平均高于对照组,且随着病情的加重呈递增水平。结论:血清胱抑素C水平可作为及早判断早期妊娠期高血压疾病患者肾脏受损的敏感指标,对避免妊娠不良结局具有重要的临床意义。
Objective: To investigate the clinical outcome of gestational hypertension in patients with serum cystatin C. Methods: Two hundred and seventy patients with gestational hypertension were divided into observation group, gestation hypertension group, mild preeclampsia group, severe preeclampsia group and eclampsia group. Select the same period of 100 healthy pregnant women as a control group. Serum cystatin C levels were measured in all pregnant women. Results: The level of serum cystatin C in each group in the observation group was higher than that in the control group, and increased with the severity of the disease. Conclusion: Serum levels of cystatin C can be used as a sensitive indicator of early renal damage in patients with hypertensive disorders in early pregnancy, and it is of great clinical significance to avoid adverse pregnancy outcomes.