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作者以高血压小儿为对象静点生理盐水,探讨静点前后心纳素(ANP)和尿Na排泄率(FE_(Na))的变动,现将结果报告如下。对象与方法以16名高血压小儿为对象(12~15岁,均为男孩),多次测定血压,多呈高血压(收缩压140mmHg以上或舒张压为90mmHg以上),经各种检查无器质性病变。检查当天早晨禁食,排尿后取卧位监护血压,90分钟后给生理盐水(15ml/kg/hr),60分钟内静点。在静点开始与结束时分别卧位采血、留尿,按成濑方法用放免法测定血浆ANP,再同时测定血清、尿Na和肌酐值,求出FE_(Na)。要了解双亲之一有否原发性高血压家族史,且在
The author of hypertensive children as the object of static saline, before and after the study to explore the changes in serum levels of ANP and urinary Na excretion rate (FE Na), the results reported below. Subjects and Methods 16 hypertensive children (12 to 15 years old, all boys), multiple determination of blood pressure, mostly high blood pressure (systolic blood pressure above 140mmHg or diastolic blood pressure above 90mmHg), after a variety of tests without appliances Qualitative lesions. Check the morning of fasting, urinate taken after monitoring blood pressure, 90 minutes after the saline (15ml / kg / hr), 60 minutes static point. At the beginning and the end of the static point, blood samples were taken from the supine position, and urine was collected. The plasma ANP was determined by radioimmunoassay according to the method of lamifloxacin, and the serum, urinary Na and creatinine values were measured simultaneously to determine FE Na. To find out if one of your parents has a family history of essential hypertension, and at