论文部分内容阅读
目的探讨小剂量血管加压素(AVP)与去甲肾上腺素(NE)治疗感染性休克的临床效果。方法选取2014年10月至2016年9月感染性休克患者102例,按照治疗方案分为两组,每组51例。对照组给予去甲肾上腺素治疗,研究组给予小剂量AVP与去甲肾上腺素治疗,比较两组乳酸清除率及血流动力学、肾功能指标水平。结果治疗后24 h,乳酸清除率、HR、MAP、肾功能指标研究组优于对照组,差异有统计学意义(P<0.05)。结论感染性休克应用AVP与NE治疗,可有效改善患者血流动力学,提高乳酸清除率,缓解肾功能损伤。
Objective To investigate the clinical effects of low dose vasopressin (AVP) and norepinephrine (NE) in the treatment of septic shock. Methods A total of 102 patients with septic shock from October 2014 to September 2016 were selected and divided into two groups according to the treatment regimen, 51 cases in each group. The control group was treated with norepinephrine. The study group was given low-dose AVP and norepinephrine treatment. The lactic acid clearance, hemodynamics and renal function were compared between the two groups. Results After 24 h of treatment, the lactic acid clearance, HR, MAP and renal function indexes were better in the study group than in the control group, with significant difference (P <0.05). Conclusions The application of AVP and NE in septic shock can effectively improve hemodynamics, increase lactic acid clearance and relieve renal dysfunction.