晚发性维生素K缺乏所致的出血,特别是颅内出血,临床上并不少见。我院于82年1月至91年4月共收治54例.此病特点是起病急,病情重,病死率高,致残者多。本组患儿经治疗痊愈34例(63％),死亡9例(16.6％),随访16例中1例死亡,6例遗留有神经系统后遗症。本病病因主要有以下三种情况:(1)摄入不足,母乳维生素K的含量仅为牛奶的1/6,因而单纬母乳喂养儿可因维生素K的 Late onset of vitamin K deficiency due to bleeding, especially intracranial hemorrhage, clinically not uncommon. Our hospital from January 1982 to April 1991 were treated 54 cases of the disease is characterized by acute onset, severe illness, high mortality, disability and more. The group of children recovered after treatment in 34 cases (63%), 9 patients died (16.6%), follow-up of 16 cases of death in 1 case, 6 cases left with nervous system sequelae. The etiology of the disease mainly in the following three conditions: (1) inadequate intake of milk vitamin K content of only 1/6 of milk, so single weft breast-fed children may be due to vitamin K