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ⅠA1期子宫颈鳞癌指镜下肿瘤浸润深度≤3mm,水平宽度≤7mm的子宫颈鳞癌。其诊断要求包含全部病变的标本,至少是切缘阴性的完整子宫颈锥切标本。由于绝大多数早期子宫颈癌患者无临床症状或体征,因此其诊断主要是通过由细胞学检查、阴道镜检查以及组织病理学组成的“三阶梯”诊断流程获得的。而对ⅠA1的处理临床上从锥切到广泛全子宫切除加盆腔淋巴结清扫并存。总之,其诊断过程复杂而严格,同时目前临床治疗方法各异,既遵循规范化指南,又体现个体化处理。本文回顾ⅠA1的诊治历史并对近年来的研究进展作一文献复习。
Cervical squamous cell carcinoma of stage ⅠA1 refers to cervical squamous carcinoma with a depth of less than 3 mm and a horizontal width of less than or equal to 7 mm. The diagnosis requires all specimens of the lesion, at least intact cervico-conus specimens. Since most early-stage cervical cancer patients have no clinical signs or symptoms, their diagnosis is mainly obtained through a “three-step” diagnostic procedure consisting of cytology, colposcopy and histopathology. The treatment of ⅠA1 clinically from conization to extensive hysterectomy plus pelvic lymph node dissection coexist. In short, the diagnostic process is complicated and strict, at the same time the clinical treatment methods are different, not only follow the normative guide, but also reflect the individualized treatment. This paper reviews the history of diagnosis and treatment of ⅠA1 and reviews the literature in recent years.