本文报告一例非分泌型骨髓瘤细胞的超微结构研究结果。用荧光抗体法检测出在90％的瘤细胞内有单克隆Ig存在。电镜观察主要发现:粗面内质网高度发达,并呈不同程度扩张;高尔基复合体明显,有很多被膜小泡。超微结构特点和临床检查结果表明:本例非分泌型骨髓瘤是属于“不分泌型”的,而不是“不产生型”的。同时,对这种类型骨髓瘤的发生机理进行了探讨。 This article reports the results of a study of the ultrastructure of non-secreting myeloma cells. Fluorescent antibody was used to detect the presence of monoclonal Ig in 90% of the tumor cells. The main findings of electron microscopy: rough endoplasmic reticulum highly developed, and showed varying degrees of expansion; significant Golgi complex, there are many capsule vesicles. Ultrastructural features and clinical examination results show that: This case of non-secretory myeloma are “not secreted”, rather than “non-producing type.” At the same time, the mechanism of this type of myeloma was discussed.