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目的：观察紫外线照射充氧自血回输（ＵＢＩ）对脑梗塞患者血浆内皮素（ＥＴ）的影响。方法：应用放射免疫分析法测定３２例脑梗塞患者应用紫外线照射充氧自血回输疗法前、后血浆内皮素的含量，并与２０例未应用ＵＢＩ疗法的脑梗塞患者及３０例健康人的血浆ＥＴ含量进行对照观察。结果：用与未用ＵＢＩ疗法的脑梗塞患者急性期血浆ＥＴ含量均显著升高，二者相比无显著性差异（Ｐ＞０．０５）。但与正常对照组相比，均有显著性差异（Ｐ＜０．０１）。治疗１４ｄ后，两组患者血浆ＥＴ含量均有显著下降，但ＵＢＩ组ＥＴ下降更明显，与非ＵＢＩ组相比，差异显著（Ｐ＜０．０１）。结论：ＵＢＩ有降低ＥＴ的作用，其对ＥＴ的影响，可能是其治疗脑梗塞的诸多机理之一。
Objective: To observe the effect of UBI on plasma endothelin (ET) in patients with cerebral infarction. Methods: The content of plasma endothelin in 32 patients with cerebral infarction before and after autologous blood oxygenation was measured by radioimmunoassay, and compared with 20 patients with cerebral infarction without UBI and 30 healthy people Plasma ET levels were compared. Results: The levels of plasma ET in acute cerebral infarction patients with and without UBI therapy were significantly increased, there was no significant difference (P> 0.05). However, compared with the normal control group, there was a significant difference (P <0.01). After 14 days of treatment, the levels of plasma ET decreased significantly in both groups, but ET decreased more significantly in UBI group than in non-UBI group (P <0.01). Conclusion: UBI has the effect of lowering ET, and its effect on ET may be one of its mechanisms for the treatment of cerebral infarction.