以草酸和异戊醇为原料,采用硫酸氢钠作催化剂合成草酸二异戊酯。考察了催化剂用量、酸醇物质的量比、带水剂用量以及反应时间等因素对产率的影响。确定最佳酯化反应的条件为:n(草酸)∶n(异戊醇)∶n(硫酸氢钠)=1∶3∶0·026,带水剂甲苯10mL,反应时间75min。产率可达96·52%。 Oxalic acid and isoamyl alcohol as raw materials, the use of sodium bisulfate as catalyst synthesis of isoamyl oxalate. The effects of the amount of catalyst, the amount of acid to alcohol, the amount of water-carrying agent and the reaction time on the yield were investigated. The optimal esterification conditions were as follows: n (oxalic acid): n (isoamyl alcohol): n (sodium bisulfate) = 1: 3: 0 026, 10 mL toluene with water agent, reaction time 75 min. The yield can reach 96.52%.