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对刚入高原（海拔３６５８ｍ拉萨）地区发生的２５例高原肺水肿（ＨＡＰＥ）、３５例急性高原反应（ＨＡＡＲ）患者和３４名健康者的肺功能变化进行了全面检测及对比研究，结果发现ＨＡＰＥ患者肺容积或仍保持平原值水平，或显著扩大，通气流速和弥散功能均降低，而耗氧增加。认为这是本病患者重度急性缺氧的直接原因，在本病的发生和发展中起重要作用。
A total of 25 pulmonary hypertension patients (HAPE), 35 patients with acute altitude sickness (HAAR) and 34 healthy subjects who had just started to enter the plateau (Lhasa at an altitude of 3658 m) were examined and compared with each other. The results showed that HAPE Patients with lung volume or still maintain the level of plain value, or significantly expanded ventilation velocity and diffuse function are reduced, while the oxygen consumption increased. Think this is the direct cause of severe acute hypoxia in patients with this disease plays an important role in the occurrence and development.