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干燥综合征(Sjogren Syndrome,简称SS)是一种以管道上皮细胞为靶器官的自家免疫性瘤。除唾液腺及泪腺受损外,全身器官的上皮性外分泌腺体均可受累,构成了临床多系统损害的表现。自从开展特异性抗体检查以来(抗SSA/SSB抗体),使过去漏诊、误诊病人大为减少,近年来国内外对该病的报道均见增多,认为该病的发病率仅次于类风湿关节炎。回顾我院77年一例死亡患者,几经周折,曾作出过多个诊断;为了提高对本病的认识,特介绍该病例于下: 张××、女、46岁、汉族、工人、77年12月16日以四肢乏力、(?)软九月余,双下肢活动失灵三天入院。
Sjogren Syndrome (SS) is a kind of autoimmune tumor targeting the ductal epithelial cells. In addition to salivary gland and lacrimal gland damage, the body parts of the epithelial exocrine glands can be involved, constitute the performance of clinical multi-system damage. Since the detection of specific antibodies (anti-SSA / SSB antibodies), the past missed diagnosis, misdiagnosis of patients greatly reduced in recent years, the domestic and international reports of the disease are seen increased, the incidence of the disease that the second only to the rheumatoid arthritis inflammation. In retrospect, one patient died in 1977 in our hospital. After several twists and turns, a number of diagnoses have been made. In order to improve our understanding of this disease, we introduce the case below: Zhang XX, F, 46, Han nationality, worker, 77 12 On the 16th with weak limbs, (?) Soft September, the activities of both lower limbs failed to hospital for three days.