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尽管抗炎剂用于急性呼吸窘迫综合征 (ARDS)动物模型有效 ,但应用于临床疗效却不理想。为此美国科学家最近成功研究出一种符合临床的 ARDS大动物模型。最初他们试图采用直肠内容物污染腹腔引起腹膜炎 ,诱发急性肺损伤 ,却未能成功。其后他们设计出肠缺血再灌注损伤复合直肠内容?
Although anti-inflammatory agents are effective in animal models of acute respiratory distress syndrome (ARDS), their clinical utility is not ideal. To this end the United States scientists recently successfully developed a clinical ARDS large animal model. Initially they tried to contaminate the peritoneal cavity using peritoneal rectal contents causing peritonitis, induced acute lung injury, but failed. Then they designed the intestine of intestinal ischemia-reperfusion injury rectal content?