本文讨论了铁吸收的调节和控制。铁由肠粘膜纹状缘摄取,在粘膜细胞基底侧面释放入门静脉系。其步骤是:铁先结合到纹状缘,再进入粘膜细胞内,并运输到门静脉循环。肠粘膜细胞摄取铁的机制有三种可能,(1)铁非特异性地结合到纹状缘;(2)纹状缘上的受体与铁有较高的亲和力;(3)肠粘膜内存在去铁铁蛋白,它粘附在纹状缘上特定的运铁蛋白受体上,铁能穿梭般地进入细胞内,粘膜细胞处理内生铁可能有两条不同途径,即铁的运输通道和铁的贮存 This article discusses the regulation and control of iron absorption. Iron is taken up by the intestinal mucosal striate rim, releasing the portal vein on the side of the mucosal cell base. The steps are: iron first binding to the striated edge, and then into the mucosal cells, and transport to the portal vein circulation. There are three possible mechanisms for uptake of iron by intestinal mucosal cells: (1) non-specific binding of iron to the striatum; (2) receptors on the striated margin have a higher affinity for iron; (3) Ferritin, which adheres to the specific transferrin receptor on the striated rim, penetrates intracellularly into the cell, and there are likely to be two distinct ways for mucosal cells to process endogenous iron, namely the iron transport pathway and the iron Storage