舍格伦综合征是一种慢性全身性自身免疫性疾病，其特点是外分泌腺(尤其是唾液腺和泪腺)的淋巴细胞浸润和炎症，导致口腔和眼部干燥。此外，多种器官系统也会受到影响，如肺、肾、肝、关节、皮肤等，同时伴有肌肉骨骼疼痛、慢性疲劳、血管炎等疾病。舍格伦综合征临床表现较复杂，病因和发病机制尚不明确，诊断标准和方法不统一，从而给临床诊断和治疗带来了一定的困难。文章就近年来舍格伦综合征诊断方法的研究进展做一总结。“,”Sjogren's syndrome is a chronic systemic autoimmune disease characterized by lymphocyte infiltration and inflammation of the exocrine glands (especially the salivary and lacrimal glands), resulting in dry mouth and eyes.In addition, a variety of organ systems can be affected, such as lung, kidney, liver, joints, skin, etc., accompanied by musculoskeletal pain, chronic fatigue, vasculitis and other diseases.The clinical manifestations of sjogren's syndrome are complex, the pathogenesis and mechanism are not clear, and the diagnostic criteria and methods are not unified, which brings certain difficulties to clinical diagnosis and treatment.This review summarizes the recent advances in diagnostic methods for Sjogren's syndrome.