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心房颤动(房颤)是常见的心律失常之一。很多研究揭示房颤与心房纤维化有关,而且有研究显示房颤病人的转化生长因子-β1的表达和活性都有所升高。因此,清楚认识转化生长因子-β1在房颤发病机制中的关系,对了解房颤发生发展过程中炎症及纤维化的作用,和指导临床治疗房颤、预防房颤复发等诸方面都非常重要。
Atrial fibrillation (AF) is one of the common arrhythmias. Many studies have revealed atrial fibrillation and atrial fibrosis, and studies have shown that patients with atrial fibrillation of transforming growth factor-β1 expression and activity have increased. Therefore, it is very important to understand the relationship between TGF-β1 and the pathogenesis of atrial fibrillation. It is important to understand the role of inflammation and fibrosis in the development and progression of atrial fibrillation and to guide the clinical treatment of atrial fibrillation. .