胃是结外淋巴瘤的好发器官,约占结外淋巴瘤的70%。原发性胃非霍奇金淋巴瘤是一组来源于B淋巴细胞及其前体细胞的病变,约占全部胃恶性肿瘤的4%～8%。过去10年,对原发性胃非霍奇金淋巴瘤患者治疗的显著变化是向非手术治疗转化。主要原因包括对其病因学的认识和最近应用清除幽门螺旋杆菌的治疗、放疗和化疗的临床研究结果。 Stomach is a good organ of extranodal lymphoma, accounting for about 70% of extranodal lymphoma. Primary gastric non-Hodgkin’s lymphoma is a group of lesions derived from B lymphocytes and their precursor cells, accounting for about 4% to 8% of all gastric malignancies. In the past 10 years, a significant change in the treatment of patients with primary gastric non-Hodgkin’s lymphoma was conversion to nonsurgical treatment. The main reasons include the understanding of their etiology and recent clinical trials of treatment of H. pylori, radiotherapy and chemotherapy.