论文部分内容阅读
目的：了解类风湿性关节炎（ＲＡ）合并骨性关节炎（ＯＡ）患者的临床特点。方法：将１９９０年１月～１９９９年６月确诊的６４例ＲＡ合并ＯＡ 患者与同期随机抽取的另６４例未合并ＯＡ的ＲＡ患者的临床和有关检查资料逐一加以比较，并作相应的统计学处理。结果：ＲＡ合并ＯＡ患者有下列特点：（１）年龄较大，体重较重，病程较长；（２）发热等全身症状、某些关节外表现以及晨僵等症状较少见；（３）伴有严重活动障碍的不对称性关节症状较多见；（４）有显著骨质疏松者较多见；（５）合并其它疾病者较常见；（６）对一般抗炎药物的治疗反应较差。结论：ＲＡ合并ＯＡ患者在临床表现、有关实验室检查、Ｘ线片所见以及对一般抗炎药物的反应等方面与一般ＲＡ患者有所不同，在临床诊断和治疗时应予注意。
Objective: To understand the clinical features of patients with rheumatoid arthritis (RA) and osteoarthritis (OA). Methods: Sixty-four RA patients with RA complicated with OA diagnosed from January 1990 to June 1999 were compared with those of 64 RA patients without OA who were randomly selected in the same period, and the corresponding statistics were compared deal with. Results: Patients with RA complicated with OA had the following characteristics: (1) older age, heavier body weight and longer course of disease; (2) systemic symptoms such as fever, some extra-articular manifestations, and morning stiffness were rare; (3) Symptoms of asymmetry with severe activity disorder are more common; (4) those with significant osteoporosis are more common; (5) patients with other diseases are more common; (6) the treatment response to general anti-inflammatory drugs difference. Conclusion: Patients with RA complicated with OA are different from those with general RA in clinical manifestations, laboratory tests, radiographs and general anti-inflammatory drugs, and should be noted in clinical diagnosis and treatment.