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本文研究了廿种黄酮化合物对环核苷酸磷酸二酯酶抑制作用。发现它们对鼠的大脑,兔的心肌,艾氏腹水癌细胞的cAMP磷酸二酯酶和cGMP磷酸二酯酶具有一定程度的选择性抑制作用。实验还表明多数黄酮甙元的抑制作用比它的黄酮甙要强。
In this paper, the inhibitory effect of flavonoids on cyclic nucleotide phosphodiesterase was studied. They were found to have a selective inhibition of the cAMP phosphodiesterase and cGMP phosphodiesterase of mouse brain, rabbit myocardium and Ehrlich ascites carcinoma cells. Experiments also showed that most of the flavone aglycone has stronger inhibition than its flavonoids.