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呋喃苯胺酸(又名速尿)是西医用于治疗因心肝肾等疾病所引起的严重水肿,特别是对其它利尿药无效的顽固水肿患者尤为适用。此药具有强效而短暂的利尿作用,但因其作用强而易致水和电解质紊乱;因其过度利尿可致低血容量、低血钠、低血氯性碱血症,尤其是严重的胃肠道反应以及主要表现为耳鸣,眩晕和耳聋的耳毒症。因此有必要用动物实验方法从中医方药中寻找利尿作用强、毒副作
Furosenic acid (also known as furosemide) is a Western medicine used to treat severe edema caused by diseases such as heart, liver, and kidney, especially for patients with stubborn edema who are ineffective for other diuretics. This drug has strong and transient diuretic effect, but because of its strong effect, it is prone to cause water and electrolyte disorders; due to its excessive diuresis can cause hypovolemia, hyponatremia, hypochloremicemia, especially serious Gastrointestinal reactions and ototoxicity mainly manifested as tinnitus, dizziness and deafness. Therefore, it is necessary to use animal experiments to search for strong diuretic effects and toxic effects from traditional Chinese medicine prescriptions.