论文部分内容阅读
目的 综合评价中国人复发性脑梗死的危险因素.方法 通过计算机文献检索(中国期刊全文数据库、维普中文科技期刊全文数据库、万方数据库),以及采用文献追溯等方法,收集国内于2011年12月前发表的关于复发性脑梗死危险因素的研究文献.采用STATA 11.0软件,应用Meta分析的方法对结果进行定量综合分析.结果 共检索到216篇文献,根据纳入与排除标准进行筛选,共有12篇文献纳入本研究,全部为病例-对照研究.累计病例1599例,对照2566例.Meta分析结果表明,性别、高血压、糖尿病、高脂血症、吸烟和年龄的合并效应量(95％可信区间)分别为1.58(1.04～ 2.39)、2.66 (2.02～3.51)、2.23 (1.70～2.93)、2.22 (1.48 ～3.32)、1.94(1.64～ 2.29)和1.58(0.55～ 2.60),经Z检验差异均有统计学意义(Z=2.16、6.95、5.82、3.87、7.68和3.02,P值均＜0.05).结论 高血压、糖尿病、高脂血症、吸烟、男性和年龄是复发性脑梗死的危险因素.“,”Objective To synthetically evaluate the risk factors of recurrent cerebral infarction in Chinese population.Methods The research literature on the risk factors of recurrent cerebral infarction from the domestic December 2011 published was collected through computers literature retrieval (China Academic Journal,VIP Chinese Science and Technology Academic Journal,Wanfang Database) and literature review.Meta-analysis method was used to synthetically and quantitatively analyze the risk factors of recurrent cerebral infarction reported in China.All of the data were analyzed by STATA 11.0 software.Results The total research literature was 216 studies,and 12 studies were enrolled in this study according to the inclusion and exclusion criteria.All case-control study.There were 1599 cases in case group,2566 cases in control group cumulatively.Meta analysis showed that the summary statistics of sex,hypertension,diabetes,hyperlipemia,smoking,age were 1.58 (1.04-2.39),2.66 (2.02-3.51),2.23 (1.70-2.93),2.22(1.48-3.32),1.94 (1.64-2.29),1.58 (0.55-2.60),respectively.There were significances in statistics (Z =2.16,6.95,5.82,3.87,7.68,3.02,respectively,P ＜ 0.05).Conclusion Hypertension,diabetes,hyperlipemia,smoking,male and age are all the risk factors of recurrent cerebral infarction.