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本文对20例星形细胞瘤,12例脑膜瘤患者的外周血淋巴细胞染色体随体联合值进行了分析,肿瘤患者的随体联合数分别为164.95和174.68,明显高于正常对照组的132.4,差异非常显著(P<0.01)。肿瘤患者随体联合数的升高主要是D组和G组染色体普遍性参与联合的频数增加所致。文章对星形细胞瘤和脑膜瘤患者随体联合值增高的意义,以及与脑膜瘤细胞22号染色体丢失的可能性关系进行了讨论。作者认为:随体联合值的增高可能是脑肿瘤发生的因素之一,它的测定可作为人群肿瘤险情监测指标。
In this paper, 20 cases of astrocytoma and 12 cases of meningioma peripheral blood lymphocyte chromosome associated with the body value was analyzed, the number of patients with cancer was 164.95 and 174.68, significantly higher than the control group, 132.4, The difference was significant (P <0.01). Tumor patients increased with the number of patients with the main group D and G chromosomes generally involved in the combination of increased frequency. The article discusses the significance of the increased joint value of astrocytoma and meningioma patients, and the possibility of loss of meningioma chromosome 22. The authors believe that: the increase of the value of satellite association may be one of the factors of brain tumors, its determination can be used as a marker of cancer risk in the population.