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目的:探讨柳胺酚对慢性乙型肝炎的疗效。方法:84例慢性乙型肝炎病人,其中42例(男性30例,女性12例;年龄42a±s7a)口服柳胺酚胶囊500mg,tid,连用8wk。另42例为对照组(男性31例,女性11例;年龄40a±8a),口服一般保肝药(强力宁、肌苷、维生素等),用8wk。结果:柳胺酚对乙型肝炎病人乏力、黄疸等症状有明显改善作用;ALT,AST,γ_GT,ALB及SB等复常率分别为90%,88%,84%,84%,90%,与对照组比较,差别有显著意义(P<0.05)。同时柳胺酚治疗组病人血清中脂质过氧化物含量明显降低,与对照组比较,差别有显著意义(P<0.05)。结论:柳胺酚可以降低病人血清中氧自由基诱导的脂质过氧化物含量,是治疗慢性乙型肝炎的有效药物
Objective: To investigate the curative effect of diazepam on chronic hepatitis B Methods: Eighty-four patients with chronic hepatitis B (42 males and 12 females; age 42a ± s7a) were given salvianidol 500 mg tid for 8 weeks. The other 42 cases were control group (31 males and 11 females; age 40a ± 8a). Oral general hepatoprotective drugs (prednisolone, inosine and vitamins) were orally administered with 8 weeks. Results: Salicylaldehyde significantly improved the symptoms of fatigue, jaundice and other symptoms of hepatitis B patients. The normal rates of ALT, AST, γ_GT, ALB and SB were 90%, 88%, 84%, 84% and 90% Compared with the control group, the difference was significant (P <0.05). At the same time, the content of lipid peroxides in the serum of patients in the control group was significantly lower than that in the control group (P <0.05). CONCLUSIONS: Salicylaldehyde reduces the level of lipid peroxidation induced by oxygen free radicals in the serum of patients and is an effective drug for the treatment of chronic hepatitis B