目的　探讨脂肪密度对比剂胃螺旋CT三维成像的可行性。方法　 2 4例受检者分 4组服用不同密度的口服脂肪对比剂 ,观察三维成像的图像质量 ,病变检出率 ,病人对脂肪对比剂的耐受性和对比剂的副作用。结果　脂肪密度对比剂的CT值达 - 140HU以上 ,CT横断位图像质量良好 ,并可以顺利进行胃肠道三维成像和CT仿真内镜检查。小组病例中 ,CT横断位图像结合三维图像 ,提高病灶检出率和定性准确性。结论　脂肪密度对比剂经过工艺的改进 ,在胃肠道螺旋CT仿真内镜和三维成像方面 ,有良好的应用前景。 Objective To investigate the feasibility of three-dimensional imaging of fatty density contrast agent gastric spiral CT. Methods Twenty-four subjects underwent oral administration of lipofectin at different densities in four groups to observe the image quality, lesion detection rate, patient tolerance to fat contrast agent and contrast agent side effects. Results The CT value of fat density contrast agent was-140HU or more, and the image of CT transverse transection had good image quality. It could successfully carry out gastrointestinal tract three-dimensional imaging and CT simulation endoscopy. In the case group, the CT transverse image combined with the three-dimensional image improved the detection rate and qualitative accuracy of the lesion. Conclusion The improvement of the technology of fat density contrast agent has a good application prospect in gastrointestinal CT endoscopy and 3D imaging.