论文部分内容阅读
目的:观察垂体后叶素联用普萘洛尔治疗肝硬化并上消化道出血的疗效,为临床合理用药提供参考。方法:选择肝硬化并上消化道出血患者86例,随机分为对照组和观察组各43例。对照组患者给予垂体后叶素治疗,观察组患者在此基础上给予普萘洛尔治疗。连续治疗5d,观察并比较两组患者临床疗效和不良反应的差异。结果:治疗后两组患者总有效率比较,观察组明显优于对照组,差异有统计学意义(P<0.05)。治疗期间两组患者不良反应发生率比较,差异无统计学意义(P>0.05)。结论:采用垂体后叶素联用普萘洛尔治疗肝硬化并上消化道出血可以取得良好的临床疗效,且不良反应少,值得临床推广应用。
Objective: To observe the effect of vasopressin combined with propranolol in the treatment of cirrhosis and upper gastrointestinal bleeding, and to provide a reference for clinical rational drug use. Methods: A total of 86 patients with cirrhosis and upper gastrointestinal bleeding were randomly divided into control group and observation group, 43 cases each. Patients in the control group were treated with pituitrin, and patients in the observation group were treated with propranolol on the basis of this. Continuous treatment of 5d, observe and compare the difference between the two groups of clinical efficacy and adverse reactions. Results: After treatment, the total effective rate of two groups of patients was significantly better than that of the control group (P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups during treatment (P> 0.05). Conclusion: The combination of pituitrin and propranolol in the treatment of liver cirrhosis and upper gastrointestinal bleeding can achieve good clinical efficacy, and fewer adverse reactions, worthy of clinical application.