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目的：探讨小儿肺炎时超氧化物歧化酶（ＳＯＤ）及丙二醛（ＭＤＡ）与免疫功能的关系。方法：对４４名支气管肺炎急性期患儿血清ＳＯＤ、ＭＤＡ、免疫球蛋白（Ｉｇ）、Ｅ花环试验（ＥＲＦＴ）、淋巴细胞转化率（ＬＣＴ）进行了测定。结果：该组患儿血清ＳＯＤ活性与正常组比较明显下降，ＭＤＡ显著上升，血清ＩｇＡ、ＩｇＧ、ＥＲＦＴ、ＬＣＴ均明显低于对照组。患儿血清ＩｇＡ与ＳＯＤ值呈直线正相关，与ＭＤＡ值呈直线负相关。结论：肺炎急性期氧自由基不仅损伤肺组织，而且损伤免疫细胞，导致免疫功能低下。
Objective: To investigate the relationship between superoxide dismutase (SOD), malondialdehyde (MDA) and immune function in children with pneumonia. Methods: Serum levels of SOD, MDA, Ig, ERF and LCT in 44 children with acute bronchial pneumonia were measured. Results: The activity of serum SOD in this group was significantly lower than that in the normal group, MDA was significantly increased, serum IgA, IgG, ERFT, LCT were significantly lower than the control group. Children with serum IgA and SOD was a positive linear correlation, and MDA values were linearly negatively correlated. Conclusion: In the acute phase of pneumonia, oxygen free radicals not only damage the lung tissue but also injure the immune cells, resulting in poor immune function.