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目的观察中西医结合治疗急性脑梗死的临床疗效。方法279例急性脑梗死患者随机分为两组,对照组140例采用西医分期治疗,治疗组139例在此基础上结合中医辨证治疗。采用神经功能缺损评分量表(CSS)、NIHSS评分、Rankin残障评级和Barthel指数进行疗效评价。结果90天试验终点时间治疗组总有效率73.38%(102/139例),优于对照组的61.43%(86/140例)(P<0.05)。NIHSS评分改善≥40%者对照组66例(47.14%),治疗组80例(57.55%);Rankin评级0-2级者对照组65例(46.43%),治疗组78例(56.12%);Barthel指数评分≥85分者对照组60例(42.86%),治疗组71例(51.08%);CSS改善≥46%者对照组为61例(43.57%),治疗组为72例(51.80%)。上述指标经统计学处理差异均有显著性,治疗组优于对照组(P<0.05)。结论中医辨证结合西医分期治疗急性脑梗死有较为明显的疗效优势。
Objective To observe the clinical efficacy of integrated traditional Chinese and western medicine in the treatment of acute cerebral infarction. Methods A total of 279 patients with acute cerebral infarction were randomly divided into two groups, 140 cases in the control group were treated by western medicine and 139 cases in the treatment group were treated with TCM syndrome differentiation. Neurological deficit score scale (CSS), NIHSS score, Rankin disability rating and Barthel index were used to evaluate the curative effect. Results The total effective rate of the 90-day trial was 73.38% (102/139) in the treatment group, which was higher than 61.43% (86/140) in the control group (P <0.05). There were 66 cases (47.14%) in the control group, 80 cases (57.55%) in the NIHSS score improvement group, 65 cases (46.43%) in the Rankin class 0-2 grade control group and 78 cases (56.12%) in the treatment group. Barthel index ≥ 85 points in the control group 60 cases (42.86%), the treatment group 71 cases (51.08%); CSS improvement ≥ 46% in the control group 61 cases (43.57%), treatment group 72 cases (51.80% . The above indexes were statistically significant differences, the treatment group was better than the control group (P <0.05). Conclusion TCM syndrome differentiation combined with Western medicine treatment of acute cerebral infarction has a more obvious therapeutic advantage.