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[目的]探讨氯化锶(89SrCl2)治疗肿瘤骨转移的疗效。[方法]采用静脉注射89SrCl24mci/人次(1.5～2.0MBq/kg体重)治疗35例肺癌骨转移患者,观察疗效及毒副反应。[结果]89SrCl2治疗后无效6例,有效17例,显效12例,总有效率为82.9%(29/35)。23例(65.7%)的患者治疗后出现Ⅰ～Ⅲ度白细胞和血小板计数下降,大多数可自行恢复。[结论]氯化锶(89SrCl2)可以安全、有效地缓解肺癌骨转移所致的疼痛。
[Objective] To investigate the therapeutic effect of strontium chloride (89SrCl2) on bone metastasis of tumor. [Method] Thirty-five patients with bone metastasis of lung cancer were treated with intravenous injection of 89SrCl24mci / person (1.5 ~ 2.0MBq / kg body weight) to observe the curative effect and toxicity. [Results] Six cases were ineffective after 89SrCl2 treatment, 17 cases were effective and 12 cases were markedly effective. The total effective rate was 82.9% (29/35). Twenty-three patients (65.7%) experienced Ⅰ ~ Ⅲ grade white blood cell count and platelet count decrease after treatment, and most of them recovered spontaneously. [Conclusion] Strontium chloride (89SrCl2) can relieve the pain caused by bone metastasis of lung cancer safely and effectively.