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林县、辉县地处河南省西北部太行山区,是我国食管癌(EC)高发区之一,该病年死亡率均在130/10万以上。病因学研究指出,营养与EC高发密切相关。流行病学回顾和前瞻调查表明,血浆维生素A(V_A)水平与癌的发生呈负相关;α-生育酚(α-V_E)
Linxian and Huixian are located in the Taihang Mountain area in the northwestern part of Henan Province and are one of the high-incidence areas for esophageal cancer (EC) in China. The annual mortality rate of the disease is 130/100,000. Etiology studies indicate that nutrition is closely related to high EC. Epidemiological review and prospective investigation show that plasma vitamin A (V_A) levels are negatively correlated with the occurrence of cancer; α-tocopherol (α-V_E)