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目的 :探讨心肌肌钙蛋白 Ⅰ (cTnI)在病毒性心肌炎诊断及预后判断中的应用。方法 :选择病毒性心肌炎患者 4 2例 ,测定血清cTnI及CK MB(肌磷酸激酶同功酶 ) ,采用超声心动图测定 ,观察心脏大小及心功能变化。结果 :(1)cTnI诊断病毒性心肌炎阳性率显著高于CK MB ;(2 )cTnI≥ 0 .2 5ng/ml患者 ,左室舒张末内径大于cTnI <0 .2 5ng/ml的患者。结论 :(1)血清cTnI作为心肌损伤指标优于CK MB ;(2 )病毒性心肌炎患者 ,血清cTnI水平高低与患者心脏大小以及远期心室功能发展有关。cTnI增高者 ,心脏呈扩大趋势 ,而心室功能测量则呈下降的趋势
Objective: To investigate the application of cardiac troponin Ⅰ (cTnI) in the diagnosis and prognosis of viral myocarditis. Methods: Forty-two patients with viral myocarditis were selected for determination of serum cTnI and CK MB (creatine phosphokinase isoenzyme). The changes of heart size and cardiac function were observed by echocardiography. Results: (1) The positive rate of cTnI in diagnosing viral myocarditis was significantly higher than CK MB. (2) In patients with cTnI≥0.25 ng / ml, the patients with left ventricular end diastolic diameter larger than cTnI <0.25 ng / ml. Conclusions: (1) Serum cTnI is better than CK MB in myocardial injury; (2) The level of cTnI in patients with viral myocarditis is related to cardiac size and long-term ventricular function in patients with viral myocarditis. Increased cTnI, the heart showed an upward trend, while ventricular function was measured downward trend