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Facile direct esterification reactions between 2′,3′-O-isopropylidene-nucleosides and Fmoc- or trityl-protected amino acids %via% N,N-dicyclohexyl-carbodiimide(DCC) mediated condensation are described. These reactions offer a mild and convenient method to synthesize aminoacylated nucleoside derivatives.
These reaction offer reactions between 2 ’, 3’-O-isopropylidene-nucleosides and Fmoc- or trityl-protected amino acids% via% N, N-dicyclohexyl-carbodiimide method to synthesize aminoacylated nucleoside derivatives.