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目的:探讨心肌肌钙蛋白I(c Tn I)、C反应蛋白(hs-CRP)和肌酸激酶同工酶(CK-MB)联合检测在儿童病毒性心肌炎(VMC)中的诊断价值。方法:病毒性心肌炎组(VMC)41例;健康对照组40例,测定两组儿童血清c Tn I、CK-MB和hs-CRP。结果:病毒性心肌炎组患儿血清c Tn I、hs-CRP和CK-MB均明显高对照组(P<0.05),三个指标联合检测的灵敏度(93.2%)、特异度(96.4%)、准确率最高(94.8%),明显高于单纯检测c Tn I、CK-MB和hs-CRP(P<0.05)。结论:联合检测c Tn I、CK-MB和hs-CRP可以儿童病毒性心肌炎的诊断准确性。
Objective: To investigate the diagnostic value of the combined detection of cardiac troponin I, c-reactive protein (hs-CRP) and creatine kinase isoenzyme (CK-MB) in children with viral myocarditis (VMC). Methods: 41 cases of viral myocarditis group (VMC); 40 healthy control group, serum cTn I, CK-MB and hs-CRP were measured in two groups. Results: The serum levels of cTn I, hs-CRP and CK-MB in the patients with viral myocarditis were significantly higher than those in the control group (93.2%), specificity (96.4%), The accuracy rate was the highest (94.8%), which was significantly higher than that of simple detection of cTn I, CK-MB and hs-CRP (P <0.05). Conclusion: The combined detection of cTn I, CK-MB and hs-CRP can be used to diagnose viral myocarditis in children.