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患者,男,65岁.因慢性支气管炎、肺心病入院.入院后使用诺氟沙星(河北辛集制药厂,批号92072)0.3mg,每日3次.口服,及氨苄青霉素治疗.用药第3日.患者感双腮部肿胀不适.查体:两侧腮腺区肿胀,轻压痛,腮腺口无红肿.次日腮部肿胀加重,面部发痒.检查见患者面红如醉酒样,面部及前胸散在米粒大红丘疹,疑为氨苄青霉素过敏引起,即予停用,而继续服用诺氟沙星并加用阿司咪唑.次日皮疹增多遍及全身,呈麻疹样损害,腮腺肿大更甚,遂疑为诺氟沙星所致,停用该药.第2天皮疹渐消,第3天腮腺肿大消退.经追询,患者从前经常眼诺氟沙星,2个月前最后一次服该药时,也曾有腮部肿胀,但停药后消退.以后住院患者又用氨苄青
Patients, male, aged 65. Due to chronic bronchitis, pulmonary heart disease admitted to the hospital after admission norfloxacin (Hebei Xinji Pharmaceutical Factory, lot number 92072) 0.3mg, 3 times a day orally, and ampicillin treatment. Day .Patients with double cheek swelling and discomfort.Checking: swelling on both sides of the parotid gland area, mild tenderness, no swelling of the parotid gland mouth swelling of the next day aggravating facial itch .Check the patient red like drunk, face and front Chest scattered rice red papules suspected of ampicillin allergy, that is to be disabled, and continue to take norfloxacin and add astemizole. The next day the rash increased throughout the body, was measles-like damage, parotid swelling even worse, Suspected to be caused by norfloxacin, the drug was discontinued .2 days rash disappeared, parotid gland enlargement subsided on day 3. After the query, the patient often eye norfloxacin, 2 months ago, the last service The drug, there had been swelling of the cheeks, but after withdrawal subsided later hospitalized patients with ampicillin