论文部分内容阅读
[目的]观察胃癌根治术前介入治疗联合围术期加味四逆泻心汤治疗对胃癌复发的影响。[方法]入选辨证为肝胃不和兼有气血痰郁并行胃癌根治术患者83例,随机分为观察组和对照组,2组患者均于胃癌根治术前行介入治疗,观察组并于围术期联合加味四逆泻心汤治疗。2组患者均术后随访3年,记录半年、1年、2年、3年生存率,半年、1年、2年、3年复发转移率。[结果]观察组、对照组分别有5例、3例患者复发后再次行手术切除。观察组的1、2、3年累计生存率分别为90.24%、80.49%、68.29%,均高于对照组(87.17%、69.23%、56.41%),2组间2、3年累计生存率差异有统计学意义(P<0.05)。观察组1、2、3年累计复发转移率(9.76%、17.07%、34.15%)均显著低于对照组(17.95%、28.21%、48.72%),P<0.05。[结论]胃癌根治术前、后服用加味四逆泻心汤联合术前介入治疗可在一定程度上降低胃癌根治术后的复发转移率,提高患者生存率。
[Objective] To observe the effect of preoperative interventional treatment of gastric cancer combined with Jia Si Ni Xie Xin Tang on the recurrence of gastric cancer. [Methods] 83 cases of gastric cancer complicated with both liver and stomach incompetence and concurrent phlegm-stasis syndrome were selected and randomly divided into observation group and control group. Both groups were treated with interventional therapy before radical gastrectomy and observation group Perioperative joint flavored Sini Xie Xin Tang treatment. The patients in both groups were followed up for 3 years. The half year, 1 year, 2 year, 3 year survival rate, half year, 1 year, 2 year and 3 year recurrence and metastasis rate were recorded. [Results] There were 5 cases in the observation group and the control group, respectively. Three cases were resected again after the recurrence. The 1, 2 and 3-year cumulative survival rates in the observation group were 90.24%, 80.49% and 68.29%, respectively, which were higher than those in the control group (87.17%, 69.23%, 56.41%). The 2 and 3-year cumulative survival rates There was statistical significance (P <0.05). The cumulative recurrence and metastasis rates in the observation group at 1, 2 and 3 years (9.76%, 17.07% and 34.15%, respectively) were significantly lower than those in the control group (17.95%, 28.21% and 48.72%, P <0.05). [Conclusions] Jiawei Sini xuespin Decoction combined with preoperative intervention before and after radical gastrectomy for gastric cancer can reduce the recurrence and metastasis rate and improve the survival rate of patients after radical gastrectomy to a certain extent.