目的:探讨新鲜移植周期与冻融胚胎移植(FET)周期妊娠结局的差异。方法:回顾性分析本中心刺激周期行新鲜胚移植(190例)和全部胚胎冷冻后再行FET(97例)周期的临床妊娠率、种植率以及流产率。结果:190例刺激周期新鲜胚胎种植后的妊娠率、种植率、流产率分别为47.4%(90/190)、30.2%(103/341)、10.0%(9/90),97例全部胚胎冷冻后行FET后的妊娠率、种植率、流产率分别为60.8%(59/97)、47.0%(86/183)、10.2%(6/59),组间妊娠率与种植率均有统计学差异(P<0.05),流产率无统计学差异(P>0.05)。结论:对于有OHSS风险等不适宜进行新鲜胚胎移植的患者,选择全部胚胎冷冻并择期进行FET,并不降低胚胎种植率和临床妊娠率,从而预防迟发型OHSS的发生,可获得更为理想的妊娠结局。 Objective: To investigate the differences of fresh pregnancy cycles and frozen-thawed embryos transplantation (FET) cycle pregnancy outcomes. Methods: The clinical pregnancy rate, implantation rate and abortion rate of the fresh embryo transfer (190 cases) and the FET (97 cases) cycles of all the embryos frozen in the center were retrospectively analyzed. Results: The pregnancy rate, implantation rate and abortion rate of fresh embryo after 190 stimulus cycles were 47.4% (90/190), 30.2% (103/341), 10.0% (9/90), 97 The pregnancy rate, implantation rate and abortion rate after FET were 60.8% (59/97), 47.0% (86/183) and 10.2% (6/59) respectively. The pregnancy rate and implantation rate were statistically (P <0.05), abortion rate was not significantly different (P> 0.05). CONCLUSIONS: For all patients with an OHSS risk that are not suitable for fresh embryo transfer, selecting all embryos for freezing and elective FET does not reduce embryo implantation rates and clinical pregnancy rates, thus preventing the occurrence of delayed OHSS and obtaining a more satisfactory Pregnancy outcome.