肾上腺素能β受体激动剂常用于严重的充血性心力衰竭的短期治疗。pirbuterol是较新的口服有效β受体激动剂,其作用持续时间长达5小时,因而试行观察其对左心室的作用可否持久。12名严重充血性心力衰竭患者口服23～30毫克pirbuterol,3小时后,心指数及左心室排出率增加35％。这对患者说来是有利的血流动力效应。每日三次,每次20毫克,连续服药1月以后,药物对左心室功能产 Adrenergic beta-agonists are often used for short-term treatment of severe congestive heart failure. Pirbuterol is a relatively new, orally active β-agonist that lasts up to 5 hours and is therefore tested for its long-lasting effect on the left ventricle. Thirteen to thirty milligrams of pirbuterol were orally administered to 12 patients with severe congestive heart failure. Three hours later, the cardiac index and left ventricular ejection rate were increased by 35%. This is a favorable hemodynamic effect for the patient. Three times a day, each 20 mg, continuous medication after January, the drug left ventricular function