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肺肿瘤是包括来自内胚层、中胚层和神经外胚层的一大类肿瘤。其中,绝大多数是起源于支气管表面上皮,支气管粘液腺体或细支气管肺泡上皮细胞的癌。光镜下通常可把肺癌分为四种基本组织学类型,即:鳞癌、腺癌、小细胞和大细胞癌。但如果用严格的光镜标准进行观察,会发现很多肺肿瘤有鳞、腺两种分化。小细胞癌可能是一种含有神经分泌型致密核心颗粒的“雀麦细胞”癌,也可能是向不同方向分化的肺癌中的一种异源癌。作者用电镜和抗角蛋白免疫过氧化酶反应仔细地对52例原发性肺癌进行了观察,结果表明:小细胞和大细胞癌为肺癌的异族,上述四
Lung tumors are a large class of tumors including endoderm, mesoderm, and neuroectodermal layers. Among them, the vast majority originate from bronchial surface epithelium, bronchial mucinous glands, or bronchioalveolar epithelial cells. Light microscopy can usually be divided into four basic histological types of lung cancer, namely: squamous cell carcinoma, adenocarcinoma, small cell and large cell carcinoma. However, if you observe with strict light microscope standards, you will find that many lung tumors have scaly and glandular differentiation. Small cell carcinoma may be a kind of cancer of the “baker’s cell” with dense core particles secreted by nerves, or it may be an allogeneic cancer in lung cancer that differentiates in different directions. The authors observed electron microscopy and anti-keratin immunoperoxidase reactions in 52 cases of primary lung cancer. The results showed that small cell and large cell carcinoma are heterogeneous groups of lung cancer.