FGFR2-TSC22D1,a novel FGFR2 fusion gene identified in a patient with colorectal cancer:A case report

来源 :世界临床病例杂志 | 被引量 : 0次 | 上传用户:gongxintao
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
BACKGROUND The FGFR signaling pathway is activated in multiple tumor types through gene amplifications,single base substitutions,or gene fusions.Novel FGFR gene fusions may represent candidate targets for the development of tyrosine kinase inhibitors.CASE
其他文献
BACKGROUND Portal venous thromboembolism caused by malignant pancreatic neuroendocrine tumor metastasis,as the initial presentation of portal hypertension and upper gastrointestinal bleeding,is a rare entity.To our knowledge,there are no reports of this e
思想政治理论课的教学目的就是要引导学生树立正确的世界观、人生观和价值观,树立正确的历史观,辩证思维地看待社会的历史发展。结合新的历史教育形式,让学生达到课程目标要求,就要结合实际,创新教学方法,调整教学设计,从现有课程教学方法中去粗取精,利用易班等网络平台,发挥网络育人功效,为中国特色社会主义培养合格的建设者和可靠的接班人。
BACKGROUND Triphalangeal thumb-polysyndactyly syndrome(TPT-PS)is a rare type of congenital limb deformity,and most studies focus on the genetics.Case reports of the sonographic characteristics of TPT-PS during pregnancy are rare.CASE SUMMARY A 30-year-old
在2012年的时候,这样一幅作品可以获得冠军,大略也是正当的事。但是九年之后的今天,再想以此获奖,应该有些难了。关键的问题,即技术的进步。在沈阳的北陵公园以及沈北新区的蒲河湿地,去年春天的时候,一群老年人坐在自己随身携带的户外折叠椅上,一手端着大茶杯,一手握着无线快门遥控器,一旁的三角架上架着高档相机,拍的就是这个戴胜鸟。只等有人喊一声“回来了”(出外捕食的回来了),立刻按动遥控器,一阵机关枪扫射一般的声音之后,大片儿就此诞生。因设备技术的提升,那图片的质量也都不错。
BACKGROUND Antisynthetase syndrome(ASS)is characterized by the presence of antisynthetase antibodies coupled with clinical findings such as fever,polymyositis-dermatomyositis and interstitial lung disease.It is,however,rare to observe ASS association with
BACKGROUND In recent years,the rate of immunosuppressed patients has increased rapidly.Invasive fungal infections usually occur in these patients,especially those who have had hematological malignances and received chemotherapy.Fusariosis is a rare pathog
BACKGROUND Currently,the advancement cancer treatment technology improves overall survival,however,adverse events are still a challenge for health professional.Genitourinary syndrome of menopause and vaginal stenosis are conditions that impact the quality
BACKGROUND There is no research on quantitative pleural line movement.In this study,we assume that tissue Doppler and its quantitative technology can quantify the pleural line movement and can be used to diagnose pneumothorax.AIM To evaluate the quantitat
Nonalcoholic fatty pancreas disease(NAFPD)is an emerging disease that has gained an increasing amount of attention in recent years.It describes fat accumulation in the pancreas with insignificant alcohol consumption,but the pathogenesis is largely unknown
BACKGROUND Intracranial hypotension(IH)is a disorder involving cerebrospinal fluid(CSF)hypovolemia due to spontaneous or traumatic spinal CSF leakage and is easily being misdiagnosed or missed,especially in these patients without the prototypical manifest