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①目的探讨焦虑症及抑郁症病人血浆中超氧化物歧化酶（ＳＯＤ）活性和丙二醛（ＭＤＡ）含量的变化。②方法采用比色法测定２４例抑郁症、２６例焦虑症病人和２３例健康人血浆ＳＯＤ活性和ＭＤＡ含量。③结果抑郁症及焦虑症病人血浆中ＳＯＤ活性明显低于对照组（ｔ＝１４．４１，２１．６１，Ｐ均＜０．００１），而ＭＤＡ含量显著升高，差异有极显著性（ｔ＝３．７３，９．９４，Ｐ均＜０．００１）。④结论抑郁症和焦虑症病人氧自由基消除能力下降
Objective To investigate the changes of plasma superoxide dismutase (SOD) and malondialdehyde (MDA) levels in patients with anxiety and depression. Methods The plasma levels of SOD and MDA in 24 patients with depression, 26 patients with anxiety and 23 healthy controls were measured by colorimetry. Results The plasma SOD activity of patients with depression and anxiety was significantly lower than that of the control group (t = 14.41, 21.61, P <0.001), while the content of MDA was significantly increased (t = 3.73,9.94, P <0.001). ④ Conclusion Depression and anxiety patients decreased ability to eliminate oxygen free radicals