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了解妊娠期葡萄糖耐量变化对妊娠结局的影响。方法：对４７０例孕前无糖尿病的孕妇，进行５０ｇ葡萄糖应激试验（５０ｇ ＣＣＴ），阳性者进一步行１００ｇ口服葡萄糖耐量试验（１００ｇ ＯＧＴＴ）。结果：５０ＧＣＴ异常的发生率为１７．０２％，妊娠期糖耐量受损（ＧＩＧＴ）的发生率为５．３１％，妊娠期糖尿病（ＧＤＭ）发生率为２．５５％。糖代谢异常患者中，巨大儿、手术产、胎膜早破、胎儿宫内窘迫及新生儿疾病等发生率显著增加；５０ｇ ＧＣＴ的血糖水平与新生儿出生体重呈正相关。提示：妊娠期的糖代谢异常可导致孕产妇及新生儿患病率增加，加强对该组孕妇的监测有可能降低母儿并发症，改善妊娠结局。
To understand the impact of changes in gestational glucose tolerance on pregnancy outcomes. Methods: 470 pregnant women without pre-conception were subjected to 50g glucose stress test (50g CCT) and 100g oral glucose tolerance test (100g OGTT). Results: The incidence of 50GCT abnormalities was 17.02%. The incidence of impaired glucose tolerance (GIGT) in pregnancy was 5.31%. The incidence of gestational diabetes mellitus (GDM) was 2.55%. Among the patients with abnormal glucose metabolism, the incidence of macrosomia, surgery, premature rupture of membranes, fetal distress and neonatal diseases increased significantly. The blood glucose level of 50g GCT was positively correlated with the birth weight of neonates. Tip: abnormal glucose metabolism during pregnancy can lead to increased prevalence of pregnant women and newborns, strengthen the monitoring of the group of pregnant women may reduce complications of maternal and child, improve pregnancy outcomes.