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内淋巴管(ED)和内淋巴囊(ES)被认为与内淋巴的吸收有关,但其转运机制在一定程度上仍很含糊,一般认为有细胞间和经细胞转运二条途径。本文采用氨咪氯吡以探索ES上皮转运机制。氨咪氯吡是一种利尿剂,特别是可抑制离子和水通过细胞原生质膜的交换。本文采用氨咪氯吡50mg/kg并稀释成10mg/ml对28只鼠作腹膜内注射,另14只鼠采用同样剂量的生理盐水注射作为对照,在注射后分别在0、15、30分钟和1、4、24小时后在全麻下致死,ES标本固定染色后在光、电显微镜下观察和照像。结果:氨咪氯吡注射立即观察ES上皮层与对照组相同,其形态正常,上皮由暗和亮细胞组成,侧细胞间隙(LIS)普遍增宽,亮细胞
Endolymphatic vessels (EDs) and endolymphatic sacs (ESs) are thought to be involved in endolymphatic absorption, but their transport mechanisms are still somewhat vague, and are thought to have two pathways, intercellular and transcellular compartments. Ammonia clopidogrel was used to explore the ES epithelial transport mechanism. Aminopyram is a diuretic, in particular, that inhibits the exchange of ions and water through the cell’s plasma membrane. In this paper, amiloride clopidogrel 50mg / kg and diluted to 10mg / ml intraperitoneal injection of 28 mice, the other 14 rats with the same dose of saline injection as a control, respectively, after injection at 0,15,30 minutes and 1,4,24 hours after death under general anesthesia, ES specimens stained after fixation under light and electron microscope and photographic. Results: Aminoclopram injection immediately observed that the ES epithelium was the same as the control group. The morphology was normal. The epithelium consisted of dark and bright cells. The lateral cell gap (LIS)