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上海市1980~1998 年报告9 例口服脊髓灰质炎疫苗相关病例(VAPP)。第1 次服苗者中VAPP的发生率每年是0~30-31/100 万,平均3-01/100 万;以0~5 岁服苗人次统计,每年发生率为0 ~5-03/100 万,平均0-52/100 万。发病者全部为男性,年龄1 ~7 月龄,均为第1 次服苗。病毒分型以Ⅲ型居多(5 例),Ⅱ型3 例,Ⅰ型1 例。服苗至发病平均潜伏期15-22 天,60 天后均残留麻痹,现有临床免疫功能检验未发现免疫功能低下或丙种球蛋白减少。
Nine cases of oral polio vaccine related cases (VAPP) were reported in Shanghai from 1980 to 1998. The incidence of VAPP in the first dose of vaccine is 0 ~ 30-31 / 1 million every year, with an average of 3-01 / 100 million. The incidence of VAPP is 0 ~ 5-03 / One million, an average of 0-52 / 100 million. The incidence of all men, aged 1 to 7 months of age, are the first service-taking. Most of the viruses were type Ⅲ (5 cases), type Ⅱ (3 cases) and type Ⅰ (1 case). The average incubation period of clothing clothes to the onset of 15-22 days, 60 days after the residual paralysis, the existing clinical immune function test found no immunocompromised or decreased gamma globulin.