药物引起的血小板减少症是一种常见的获得性出血紊乱病。作者应用了Kelton等最近(1981)提出的经典的抗球蛋白消耗分析的微量滴定度改良法进行血清血小板可结合的IgG(SPBIgG)的方法,对32位药物引起的血小板减少症病人的抗血小板活性的IgG抗体做了研究、使用的药物有:阿司匹林、去甲氨基比林、抗生素、硫酰胺、地高辛、肝素和鹅脱氧胆酸。32例被检病人中20例血小板数明显下降(<50.000/ml),12 Drug-induced thrombocytopenia is a common acquired bleeding disorder. The authors applied the classical method of microtitre titration improved by Kelton et al. (1981) to determine serum albumin-binding IgG (SPBIgG) in patients with thrombocytopenia caused by thrombocytopenia Active IgG antibodies were investigated using aspirin, desmethin, antibiotics, sulfamides, digoxigenin, heparin and chenodeoxycholic acid. The number of platelets in 20 of the 32 patients tested was significantly decreased (<50.000 / ml), 12