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1975年6月至1976年4月作者测定了本院收治的食管癌患者外周血的淋巴细胞对食管癌细胞的毒性,其阳性率为54％。与此同时,另一个研究组用食管癌3MKCl提取物做自体皮试,50％出现阳性反应。两个实验的符合率达80％。两组实验结果提示食管癌可能具有能引起肿瘤宿主的细胞免疫反应的相关抗原。最近对7年半以后曾作淋巴细胞毒性测定的32例患者复查,发现细胞毒试验阴性者17/18例已死亡,然而
From June 1975 to April 1976, the authors measured the toxicity of peripheral blood lymphocytes of esophageal cancer patients treated in our hospital to esophageal cancer cells, with a positive rate of 54%. In the meantime, another study group used autologous skin test with esophageal cancer 3MKCl extract, with a 50% positive response. The coincidence rate of two experiments was 80%. Two sets of experimental results suggest that esophageal cancer may have related antigens that can induce the cellular immune response of the tumor host. A review of 32 patients recently tested for lymphocytotoxicity after 7 years and a half found that 17 of 18 patients who tested negative for cytotoxicity had died,